Objective,2,To investigate the sterilization of OLYMPUS flexible endoscopes with a low temperature steam formaldehyde sterilizer of a national brand model FS-130 and to verify its compatibility.,Methods,2,Eight flexible endoscopes sterilized in our hospital central sterile supply department from June 2020 to December 2022, with a total of 1836 batches sterilization data, were selected as a study group test and evaluated for sterilization effectiveness, compatibility and appearance.,Results,2,The eight flexible endoscopes used in the test, after the low temperature steam formaldehyde sterilization test, material compatibility is good, there is no aging of the rubber, adhesive peeling and other problems, all physical, chemical and biological monitoring during the test were qualified, there is no blurred imaging, insensitive operation and other abnormal performance conditions.,Conclusion,2,OLYMPUS flexible fiber optic endoscopes and electronic endoscopes can be sterilized by a national brand model FS-130 low temperature steam formaldehyde sterilizer, and the sterilization effectiveness as well as the compatibility and functionality of the flexible endoscopes themselves can be guaranteed.