Objective,2,To improve the qualification rate of small dental instruments cleaning by quality control circle (QCC) application.,Methods,2,The QCC activity with the theme of "improving the qualification rate of small dental instruments cleaning" was carried out to investigate the current situation of small dental instruments cleaning in the Central Sterile Supply Department (CSSD) of our hospital, analyze the main reasons, set targets, formulate countermeasures, organize implementation and evaluate the effect. A total of 4074 small dental instruments cleaned from April 1 to 24, 2021 by CSSD (before the QCC activity) were selected as the control group, and 2784 small dental instruments cleaned from August 9 to 25, 2021 (after the QCC activity) were selected as the experimental group, and the cleaning qualification rates of the two groups were compared and analyzed.,Results,2,Before the implementation of QCC, the qualification rate of small dental instruments cleaning was 64.29%; after the implementation of QCC, the qualification rate of small dental instruments cleaning was 91.13%, and the difference was statistically significant (,P,<,0.01). The qualification rate of cleaning was increased by 26.84%, and the target achievement rate was 118.34%.,Conclusion,2,Carrying out the QCC activity can improve the qualification rate of small dental instruments cleaning, enhance the ability of employees to use QCC management tools to solve practical issues, reduce occurrence of loss or confusion of small dental instruments, and facilitate their management. It is worthy of clinical application.