Objective,2,To explore the application effect of SWOT analysis in the implementation of centralized management of stomatology instruments.,Methods,2,To establish a special work promotion team, apply SWOT analysis to the implementation of centralized stomatological appliance management, fully grasp the opportunities and challenges, and take corresponding countermeasures against the disadvantages in the implementation of centralized stomatological appliance management to promote the smooth development of the work.,Results,2,The centralized management of stomatological instruments was carried out smoothly, the cleaning qualification rate of instruments rose from 70.6% up to 98.4%, the packaging sterilization qualification rate rose from 86.4% up to 99.2%, and the satisfaction rate of instrument handling supply increased.,Conclusion,2,The use of SWOT analysis in the implementation of centralized instrument handling management in the sterile supply centre allows managers to make full use of the advantageous conditions, identify the disadvantages in the work, adopt effective countermeasures in a purposeful and planned manner, promote the efficient operation of the centralized instrument management mode in the outpatient dental department, improve the quality of instrument handling and service satisfaction, and promote the development of the subspecialty.