Objective,2,To study the effect of different cleaning methods on the rapid removal of eschared laparoscopic surgical instruments.,Methods,2,One hundred and two eschared laparoscopic surgical instruments recovered after daily use from 13 April 2020 to 30 April 2020 were randomly and numerically divided into two groups for the study: 493 in the conventional group, using the method of multi-enzyme detergent immersion + ultrasound with enzyme-containing ultrasonic cleaner + steam cleaner; 509 in the experimental group, using the method of multi-enzyme detergent immersion + ready-to-use acid detergent immersion + Steam cleaning machine method.,Results,2,493 endoscopic instruments in the conventional group and 509 instruments in the experimental group were sampled, and 388 instruments in the conventional group were tested by visual inspection, with a pass rate of 79.67%, and 464 instruments in the experimental group, with a pass rate of 91.14%. In terms of cleaning time, 493 devices in the conventional group (106 bipolar, 122 electrocoagulation hooks, 93 ultrasonic knives, 71 ligasures, 101 robotic devices) took 1788-2158 hours to clean, while 509 devices in the experimental group (113 bipolar, 135 electrocoagulation hooks, 101 ultrasonic knives, 68 ligasures, 92 robotic devices) took 56-319 hours to clean. The test group took significantly less time to clean than the conventional group, and the difference was statistically significant (,p,<,0.05).,Conclusion,2,The use of multi-enzyme detergent soaking + ready-to-use acid detergent soaking + steam cleaning machine can greatly reduce the cleaning time of eschar desiccated laparoscopic instruments, effectively guarantee the cleaning quality and improve the turnover of laparoscopic surgical instruments.