Efficacy of Antimicrobial Materials on Environmental Surfaces: A 12-Week Prospective Controlled Trial

Caiyun Chen; Hao Liu; Yongxia Gao; Jing Zhou; Xiang Zhang; Bo Liu

doi:10.11910/j.issn.2791-2043.2025.4.07

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Efficacy of Antimicrobial Materials on Environmental Surfaces: A 12-Week Prospective Controlled Trial

MONOGRAPHIC STUDY | Updated：2026-04-21

- Efficacy of Antimicrobial Materials on Environmental Surfaces: A 12-Week Prospective Controlled Trial
- Sterile Supply Vol. 4, Issue 4, (2025)
- Affiliations：
  
  1.Department of Pharmacy, The First Affiliated Hospital of Nanjing Medical University
  2.Department of infection, Children's Hospital of Nanjing Medical University
  3.Department of Infectious Diseases, The First Affiliated Hospital of Nanjing Medical University
  4.Department of Critical Care Medicine, The First Affiliated Hospital of Nanjing Medical University
  5.Department of Infection Management, The First Affiliated Hospital of Nanjing Medical University
  6.Medical Administration Department, The First Affiliated Hospital of Nanjing Medical University
- Author bio：
  
  Email: cloudccy@163.com
  Email: liuhaoanhui@126.com
  Xiang Zhang at jsphzx@163.com
  Bo Liu at liusanbo@163.com
- Funds：
- DOI：10.11910/j.issn.2791-2043.2025.4.07
  CLC：
- Published：15 December 2025
- Accepted：
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Chen Caiyun,Liu Hao,Gao Yongxia,et al.Efficacy of Antimicrobial Materials on Environmental Surfaces: A 12-Week Prospective Controlled Trial[J].Sterile Supply,2025,04(04):289-295.
DOI：

Chen Caiyun,Liu Hao,Gao Yongxia,et al.Efficacy of Antimicrobial Materials on Environmental Surfaces: A 12-Week Prospective Controlled Trial[J].Sterile Supply,2025,04(04):289-295. DOI： 10.11910/j.issn.2791-2043.2025.4.07.

摘要

Abstract

Objective

This study aims to evaluate the sustained antimicrobial efficacy of antimicrobial materials on high-touch surfaces in an intensive care unit (ICU).

Methods

A prospective

controlled study was employed. An experimental group (surfaces coated with antimicrobial material) and a control group (surfaces receiving routine disinfection) were established in an ICU. Environmental surface sampling was performed at weeks 1

and 12

with microbial contamination measured as colony-forming units per square centimeter (CFU/cm

Results

Surface contamination was significantly lower in the experimental group at all assessment time points versus the control (Week 1: 0.42 vs. 2.31 CFU/cm

0.01)

with all experimental surfaces complying with the Class II specification (≤5 CFU/cm

) specified in the national standard

Hygienic standard for disinfection in hospitals

(GB 15982—2012). The experimental group showed a trend of initial slight increase and subsequent decrease in CFU counts

with overall contamination remaining low.

Conclusion

Antimicrobial materials can maintain continuous microbial control on environmental surfaces independently of chemical disinfectants

and offer a valuable supplementary measure for integration into healthcare infection prevention strategies.

关键词

Keywords

references

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