A Meta-Analysis Comparing Two Disinfectants for Digestive Endoscope Disinfection

Jingna Sun; Na Hui; Yue Zhang

doi:10.11910/j.issn.2791-2043.2025.3.04

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A Meta-Analysis Comparing Two Disinfectants for Digestive Endoscope Disinfection

REVIEW ARTICLES | Updated：2026-01-31

- A Meta-Analysis Comparing Two Disinfectants for Digestive Endoscope Disinfection
- Sterile Supply Vol. 4, Issue 3, (2025)
- Affiliations：
  
  Nursing Department of Xijing Hospital of Air Force Military Medical University, Xi’an, Shaanxi 710000, China
- Author bio：
  
  Jingna Sun at 2829873179@qq.com
- Funds：
- DOI：10.11910/j.issn.2791-2043.2025.3.04
  CLC：
- Published：15 October 2025
- Accepted：
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Sun Jingna,Hui Na,Zhang Yue.A Meta-Analysis Comparing Two Disinfectants for Digestive Endoscope Disinfection[J].Sterile Supply,2025,04(03):159-165.
DOI：

Sun Jingna,Hui Na,Zhang Yue.A Meta-Analysis Comparing Two Disinfectants for Digestive Endoscope Disinfection[J].Sterile Supply,2025,04(03):159-165. DOI： 10.11910/j.issn.2791-2043.2025.3.04.

摘要

Abstract

Objective

This meta-analysis aimed to systematically compare the disinfection efficacy of Peracetic Acid (PAA) and Phthalaldehyde (OPA) for digestive endoscopes.

Methods

Randomized controlled trials (RCTs) comparing PAA and OPA for digestive endoscope disinfection were independently identified by two investigators through systematic searches of databases

including Wanfang Data

China National Knowledge Infrastructure (CNKI)

VIP Database

Chinese Biomedical Database (CBM)

PubMed

Cochrane Library

Web of Science

and Embase. Study selection

data extraction

and quality assessment of included studies were also performed by them independently. A meta-analysis was conducted using RevMan 5.4 software on studies that met the predefined quality criteria.

Results

Seven RCTs involving a total of 1038 digestive endoscope procedures were included. The meta-analysis demonstrated a significantly higher disinfection qualification rate for PAA compared to OPA (OR=2.31

95% CI: 1.04-5.12

=0.04). No statistically significant differences were found between the two disinfectants regarding post-disinfection bacterial colony counts or associated disinfection costs (

0.05 for both).

Conclusion

Immersion in PAA provides superior disinfection efficacy for digestive endoscopes compared to OPA.

关键词

Keywords

references

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