Exploration of Most Difficult-to-Sterilize Location in Pulse Vacuum Sterilizers

Ling Fang; Qiang Zhang; Yu Liu; Ling Liu

doi:10.11910/j.issn.2791-2043.2025.1.06

Your Location：

Home >

Browse articles >

Exploration of Most Difficult-to-Sterilize Location in Pulse Vacuum Sterilizers

MONOGRAPHIC STUDY | Updated：2025-12-02

- Exploration of Most Difficult-to-Sterilize Location in Pulse Vacuum Sterilizers
- Sterile Supply Vol. 4, Issue 1, (2025)
- Affiliations：
  
  Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei, Wuhan, 430030, China
- Author bio：
  
  Fang Ling, Unit: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology; Address: 1277 Jiefang Avenue, Jianghan District, Wuhan City, Hubei Province, China; Postal code: 430030; Email:287812165@qq.com
  Zhang Qiang at zhangqiang@whuh.com
- Funds：
- DOI：10.11910/j.issn.2791-2043.2025.1.06
  CLC：
- Published：15 June 2025
- Accepted：
Scan QR Code
Ling Fang,Qiang Zhang,Yu Liu,et al.Exploration of Most Difficult-to-Sterilize Location in Pulse Vacuum Sterilizers[J].Sterile Supply,2025,04(01):44-48.
DOI：

Ling Fang,Qiang Zhang,Yu Liu,et al.Exploration of Most Difficult-to-Sterilize Location in Pulse Vacuum Sterilizers[J].Sterile Supply,2025,04(01):44-48. DOI： 10.11910/j.issn.2791-2043.2025.1.06.

摘要

Abstract

Objective

The present study aims to explore the most difficult-to-sterilize location within the chamber of pulse vacuum sterilizers

providing a reference for the placement of biological monitoring packs during routine operation.

Method

Using temperature and pressure detectors

temperature testing was conducted on 16 identical models of pulse vacuum sterilizers in four Grade Ⅲ-A hospitals under different loading conditions

including no-load

instrument load

and dressing load. The location of the slowest heating point within the sterilizer chamber was determined.

Result

Statistics from 43 batches

totaling 258 data points show that the slowest heating point appeared most frequently at the lower level of the sterilizing rack

near the loading door

occurring 29 times

accounting for 67.44%; the location at the upper level of the sterilizing rack near the loading door occurred 14 times

accounting for 32.56%.

Conclusion

The most difficult-to-sterilize locations for this model of pulse vacuum sterilizer were near the loading side door

with the highest probability at the lower-level location near the door. Therefore

it is recommended to place the biological monitoring pack at the lower level of the sterilizing rack

near the loading side door

during routine biological monitoring.

关键词

Keywords

references

NIU Z D , LU Y H , LIU W J , et al . Validation of sterilization effect of pulsant vacuum sterilizer [J ] . China Pharm , 2022 , 31 ( 22 ): 75 - 77 .

National Health Industry Standard of the People’s Republic of China . Central sterile supply department (CSSD) - Parts 1-3: Management Standards ( WS310.1-2016 ) (2016 Edition) [S ] . 2016 .

Jr YANG J , ROBBINS M , REILLY J , et al . The clinical effect of a rotator cuff retear: a meta-analysis of arthroscopic single-row and double-row repairs [J ] . Am J Sports Med , 2017 , 45 ( 3 ): 733 - 741 .

CHEN M , XU W , DONG Q R , et al . Outcomes of single-row versus double-row arthroscopic rotator cuff repair: a systematic review and meta-analysis of current evidence [J ] . Arthroscopy , 2013 , 29 ( 8 ): 1437 - 1449 .

DEHAAN A M , AXELRAD T W , KAYE E , et al . Does double-row rotator cuff repair improve functional outcome of patients compared with single-row technique?A systematic review [J ] . Am J Sports Med , 2012 , 40 ( 5 ): 1176 - 1185 .

General Administration of Quality Supervision , Inspection and Quarantine of the People’s Republic of China , Standardization Administration of China . Technical requirements for large steam sterilizers—Automatic type ( GB 8599—2008 ) [S ] . Beijing : General Administration of Quality Supervision, Inspection and Quarantine of the People’s Republic of China, Standardization Administration of China , 2008 .

GUAN L J , WEI J G , YANG L F . Study of sterilization parameters monitoring of external equipment during the sterilization process [J ] . Chongqing Medicine , 2021 , 50 ( 16 ): 2797 - 2799 .

China Pharmaceutical Association of Plant Engineering , Parenteral Drug Association (PDA) . PDA Technical Report No . 1 , Validation of Moist Heat Sterilization Processes : Cycle Design, Development, Qualification and Ongoing Control . 2007: Supplement Vol . 1 No. S-1.

SHEN J W , ZHANG Y X . Validation of heat distribution in autoclave [J ] . Pharm Eng Des , 2009 , 30 ( 6 ): 24 - 26 .

CHAI H R , YANG L L , ZHANG L . Study on testing sterilization performance of pulse vacuum sterilizer in hospital by temperature and pressure detector [J ] . J Hebei Med Univ , 2018 , 39 ( 6 ): 725 - 728 .

GU J H , ZHANG J Y , LU L X , et al . Application of high temperature and high pressure recorder in monitoring of vacuum pressure steam sterilizer [J ] . Chin J Nosocomiology , 2016 , 26 ( 21 ): 5022 - 5024 .

Views

Downloads

CSCD

Alert me when the article has been cited

Submit

Tools

Publicity Resources

No data

Related Author

No data

Related Institution

No data

⁰