Study on a novel monitoring method of residual protein in cleaning effect of reusable medical devices

Junjun Shi; Yusheng Li; Yiqing Chen; Wei Wang

doi:10.11910/j.issn.2791-2043.2023.1.05

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Study on a novel monitoring method of residual protein in cleaning effect of reusable medical devices

MONOGRAPHIC STUDY | Updated：2026-01-13

- Study on a novel monitoring method of residual protein in cleaning effect of reusable medical devices
- Sterile Supply Vol. 2, Issue 1, (2023)
- Affiliations：
  
  Nanjing Jusha Medical Technology Co., Ltd., 210000, Nanjing, Jiangsu, China
- Author bio：
- Funds：
- DOI：10.11910/j.issn.2791-2043.2023.1.05
  CLC：
- Published：15 March 2023
- Accepted：
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Shi Junjun,Li Yusheng,Chen Yiqing,et al.Study on a novel monitoring method of residual protein in cleaning effect of reusable medical devices[J].Sterile Supply,2023,02(01):34-40.
DOI：

Shi Junjun,Li Yusheng,Chen Yiqing,et al.Study on a novel monitoring method of residual protein in cleaning effect of reusable medical devices[J].Sterile Supply,2023,02(01):34-40. DOI： 10.11910/j.issn.2791-2043.2023.1.05.

摘要

Abstract

Objective

To study the application of a new detection method of residual protein.

Methods

The detection range and anti-interference detection ability of the new residual protein monitoring method were tested and the data was compared with the UV-Vis OPA method. The influence of the differences among five different types of protein on the two detection results and the detection rate of residual protein in different devices were tested.

Results

The new residual protein detection method's detection limit was 0.1μg/mL

and it was insensitive to non-oxidizing interferents. The difference in protein is low

and the Cv value is 13.74. The detection rate of protein was better than that of UV-Vis OPA method

and the difference was significant (P > 0.01).

Conclusion

Compared with UV-vis OPA method

the new detection method of residual protein has higher sensitivity

a more comprehensive detection range

and a lower difference between proteins. It is effective to monitor the residual protein in device cleaning

and it is worth popularizing.

关键词

Keywords

references

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