Latest Issue
      Issue 1 ， 2023

        GUIDE INTERPRETATION

      • Danting Luo,Yubin Zhang,Yihua Zhao,Yan Zhang,Xiaohong Zheng,Hua Qian
        Vol. 2, Issue 1, (2023) DOI: 10.11910/j.issn.2791-2043.2023.1.01
        Abstract：The ongoing COVID-19 pandemic reveals the shortages of our worrisome indoor air quality. Indoor air quality monitoring systems provide a promising strategy, and a systematic guideline for monitoring systems is vital. The new publication of DB32/T 4176-2021 specification[1] is the first systematic guideline to help standardize air quality monitoring systems in public spaces. In order to facilitate the implementation and promotion of this specification, the revision background, drafting principles, and basis for the preparation and revision of main technical indicators were interpreted. Applying this specification helps to improve the operation and maintenance level, improve the indoor air quality of public buildings, and ensure the respiratory health of every occupant.  
        Keywords：Indoor air quality monitoring system;Public buildings;Interpretation   
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        Published：2023-03-27

        REVIEW ARTICLES

      • Han Jiang,Ying Huang,Jingyi Lv,Xiaosong Wu,Jinchen Wang,Wei Shao
        Vol. 2, Issue 1, (2023) DOI: 10.11910/j.issn.2791-2043.2023.1.02
        Abstract：This paper reviews and summarizes the literature on the current situation of hospital disinfection, disinfection methods, disinfection management, and monitoring and evaluation of disinfection effects under the new coronavirus pneumonia epidemic, with the aim of providing a basis for the development of scientific disinfection protocols when medical institutions respond to public health emergencies in the future, and promoting the scientific application of disinfection methods in medical institutions at all levels for the purpose of regular epidemic prevention and control.  
        Keywords：Corona virus disease 2019 pneumonia;Healthcare institutions;disinfection;Research progress   
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        Published：2023-03-27
      • Yusheng Li,Junjun Shi,Yiqing Chen,Wei Wang
        Vol. 2, Issue 1, (2023) DOI: 10.11910/j.issn.2791-2043.2023.1.03
        Abstract：Endoscopic retrograde cholangiopancreatography (ERCP) with duodenoscope has become an important treatment for pancreatic and biliary diseases. However, the report of duodenoscopy-related infection in ERCP practice has never stopped, and it has attracted much attention in recent years. With the continuous concern about duodenoscopy infection, supplemental measures to enhance duodenoscope reprocessing have been released, and relevant societies have updated the guidelines accordingly, which has also accelerated the innovative design and optimization of duodenoscopy by manufacturers. To help infection control professionals understand the current situation and research progress of duodenoscopy reprocessing, this review reviews it from the following aspects, including whether duodenoscopy should be disinfected or sterilized, the main causes of exogenous infection of duodenoscopy, the effectiveness of supplemental measures, the effectiveness of partial or total disposable duodenoscopy, health economy and environmental impact.  
        Keywords：Duodenoscope;ERCP;Single-use duodenoscope;Infection control;High level-disinfection   
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        Published：2023-03-27

        MONOGRAPHIC STUDY

      • Pingle Zhou
        Vol. 2, Issue 1, (2023) DOI: 10.11910/j.issn.2791-2043.2023.1.04
        Abstract：ObjectiveTo verify the virus killing efficiency, stability and clinical safety of a composite hand & skin antiseptics containing chlorhexidine.MethodsThe suspension inactivation test, physical & chemical analysis, accelerated aging study and animal toxicity test were executed to evaluate the virus killing efficiency, stability and clinical safety of the composite hand & skin antiseptics.ResultsThe composite hand & skin antiseptics containing 0.45 % gluconic acid gluconate, 75 % ethanol and synergists was used for 1 min, the average inactivation of poliovirus type I (PV-I) and EV71 enterovirus in suspension were both >4.00. The sealed package was stored at 37 °C for 3 months, and its active ingredient decline rate was <10%. The composite hand & skin antiseptics is actually non-toxic; it has no micronucleus effect on mouse bone marrow polychromatic red blood cells; it has no irritation to white rabbit in multiple intact skin test.ConclusionThe composite hand & skin antiseptics has a good killing performance on viruses with good stability. It is safe to use for skin and hand disinfection.  
        Keywords：Composite hand antiseptics;Chlorhexidine;Ethanol;virus;Inactivation efficiency;Stability, Clinical safety   
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        Published：2023-03-27
      • Junjun Shi,Yusheng Li,Yiqing Chen,Wei Wang
        Vol. 2, Issue 1, (2023) DOI: 10.11910/j.issn.2791-2043.2023.1.05
        Abstract：ObjectiveTo study the application of a new detection method of residual protein.MethodsThe detection range and anti-interference detection ability of the new residual protein monitoring method were tested and the data was compared with the UV-Vis OPA method. The influence of the differences among five different types of protein on the two detection results and the detection rate of residual protein in different devices were tested.ResultsThe new residual protein detection method's detection limit was 0.1μg/mL, and it was insensitive to non-oxidizing interferents. The difference in protein is low, and the Cv value is 13.74. The detection rate of protein was better than that of UV-Vis OPA method, and the difference was significant (P > 0.01).ConclusionCompared with UV-vis OPA method, the new detection method of residual protein has higher sensitivity, a more comprehensive detection range, and a lower difference between proteins. It is effective to monitor the residual protein in device cleaning, and it is worth popularizing.  
        Keywords：Reusable medical devices;Residual protein test;New type;Monitor   
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        Published：2023-03-27
      • Aihua Liu
        Vol. 2, Issue 1, (2023) DOI: 10.11910/j.issn.2791-2043.2023.1.06
        Abstract：ObjectiveTo investigate the sterilization of OLYMPUS flexible endoscopes with a low temperature steam formaldehyde sterilizer of a national brand model FS-130 and to verify its compatibility.MethodsEight flexible endoscopes sterilized in our hospital central sterile supply department from June 2020 to December 2022, with a total of 1836 batches sterilization data, were selected as a study group test and evaluated for sterilization effectiveness, compatibility and appearance.ResultsThe eight flexible endoscopes used in the test, after the low temperature steam formaldehyde sterilization test, material compatibility is good, there is no aging of the rubber, adhesive peeling and other problems, all physical, chemical and biological monitoring during the test were qualified, there is no blurred imaging, insensitive operation and other abnormal performance conditions.ConclusionOLYMPUS flexible fiber optic endoscopes and electronic endoscopes can be sterilized by a national brand model FS-130 low temperature steam formaldehyde sterilizer, and the sterilization effectiveness as well as the compatibility and functionality of the flexible endoscopes themselves can be guaranteed.  
        Keywords：Low temperature steam formaldehyde sterilizer;Flexible endoscope;Sterilization;Compatibility   
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        Published：2023-03-27
      • Jie Zhao,Rongkai Xu,Xunchong Fan
        Vol. 2, Issue 1, (2023) DOI: 10.11910/j.issn.2791-2043.2023.1.07
        Abstract：PurposeTo quantitatively analyze the effect of starting the pressure steam sterilizer in different startup conditions on BD test results, and to provide operational suggestions for medical units.MethodsWhen the jacket pressure of the pressure steam sterilizer reached the set value before daily sterilization, the BD test program was directly run and set as the control group. When the jacket pressure of the pressure steam sterilizer reached the set value before daily sterilization, the "no-load preheating" program was first run, followed by the BD test program, and set as the experimental group. In the two groups of the sterilization process, 13 sterilization PCDs with increasing difficulty of steam penetration, plus five kinds of chemical indicators and BD test package were placed. After sterilization, record the value of the most difficult PCD and the qualification of the BD test package.ResultsThe average value of the most difficult PCD passed by the control group was 4.24, and the average value of the most difficult PCD passed by the experimental group was 8.32. The qualified rate of BD in the control group was 89%, and that in the experimental group was 100%; P<0.05, with statistical significance.ConclusionPreheating without load can improve the sterilization performance of pressure steam sterilizer before BD test every day.  
        Keywords：No-load preheatin;PCD;BD;Performance;Pressure steam sterilizer   
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        Published：2023-03-27
      • Chunping Chen
        Vol. 2, Issue 1, (2023) DOI: 10.11910/j.issn.2791-2043.2023.1.08
        Abstract：To explore the effect of medical failure mode and effect analysis (HFMEA) in the quality management of gynecological laparoscopic instrument cleaning.MethodsUsing HFMEA, we analyzed the possible influencing factors of laparoscopic instrument cleaning failure, identified potential failure modes, developed improvement measures, and conducted prospective interventions. The risk priority index (RPN) values of the top 4 failure modes were significantly lower than those before the implementation of the improvement program, and the cleaning qualification rate of laparoscopic instruments increased from 94.9% to 99.3% (P < 0.05).ConclusionApplying HFMEA to manage the quality of gynecological laparoscopic cleaning can prospectively analyze and identify various aspects of the laparoscopic cleaning process that affect the cleaning quality, optimize the process in a targeted manner, and improve the quality of laparoscopic instrument cleaning.  
        Keywords：HFMEA;laparoscopic instruments;cleaning quality;Risk priority index   
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        Published：2023-03-27
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