Research and application effect analysis on infection prevention and control quality improvement in central sterile supply department based on HFMEA and SPO methods

Mengxin Lyu; Zhiying Teng; Min Shi; Min Wang; Meng Wang

doi:10.11910/j.issn.2791-2043.2025.2.05

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Research and application effect analysis on infection prevention and control quality improvement in central sterile supply department based on HFMEA and SPO methods

MONOGRAPHIC STUDY | Updated：2026-02-06

- Research and application effect analysis on infection prevention and control quality improvement in central sterile supply department based on HFMEA and SPO methods
- Sterile Supply Vol. 4, Issue 2, (2025)
- Affiliations：
  
  The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China
- Author bio：
  
  Mengxin Lyu, e-mail: 719576641@qq.com
  Min Shi at z-litao@163.com
- Funds：
- DOI：10.11910/j.issn.2791-2043.2025.2.05
  CLC：
- Published：15 August 2025
- Accepted：
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Lyu Mengxin,Teng Zhiying,Shi Min,et al.Research and application effect analysis on infection prevention and control quality improvement in central sterile supply department based on HFMEA and SPO methods[J].Sterile Supply,2025,04(02):92-100.
DOI：

Lyu Mengxin,Teng Zhiying,Shi Min,et al.Research and application effect analysis on infection prevention and control quality improvement in central sterile supply department based on HFMEA and SPO methods[J].Sterile Supply,2025,04(02):92-100. DOI： 10.11910/j.issn.2791-2043.2025.2.05.

摘要

Abstract

Objective

The present study aims to investigate the application efficacy of the Supply-Process-Output (SPO) and Healthcare Failure Mode and Effects Analysis (HFMEA) methodologies in infection prevention and quality management practices within a central sterile supply department (CSSD).

Methods

Based on literature reviews and the specific circumstances in an institution

an integrated systemic prevention framework was constructed by combining HFMEA-based failure mode analysis with the SPO model. A risk assessment scale for infection control in CSSD was developed to identify and analyze potential failure modes and their consequences

thereby formulating targeted quality control measures and mitigating hospital-acquired infection (HAI) risks.

Results

Comparative data before (March to June 2024) and after (October to December 2024) implementation demonstrated significant improvements in key metrics

including instrument cleaning compliance rate

equipment failure frequency

emergency item processing efficiency

and clinical department satisfaction scores. The Risk Priority Numbers (RPN) were markedly reduced (

0.01) with statistically significant differences.

Conclusion

A scientific and systematic assessment of HAI risks in CSSD based on the HFMEA and SPO methodologies and in consideration of actual operational conditions effectively mitigates infection risks and enhances medical safety and quality assurance.

关键词

Keywords

references

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