Stability study of medical peracetic acid during using period

Bing Sheng; Yuxin Su; Rui Chen; Zhiping Liu; Yang Liu; Qingdong Ye; Zuming Mao; Xiumei Deng

doi:10.11910/j.issn.2791-2043.2024.1.04

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Stability study of medical peracetic acid during using period

MONOGRAPHIC STUDY | Updated：2024-05-30

- Stability study of medical peracetic acid during using period
- Sterile Supply Vol. 3, Issue 1, (2024)
- Affiliations：
  
  1.Xiang'an Hospital of Xiamen University, Xiameng, Fujian, 361102, China
  2.Zhongguancun International Medical Inspection and Certification Co., Ltd.
  3.Henan Sanqiang Medical Instruments Co., Ltd.
  4.Hunan Dongzi Huiyue Medical Technology Co., Ltd.
  5.First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510062, China
- Author bio：
- Funds：
- DOI：10.11910/j.issn.2791-2043.2024.1.04
  CLC：
- Published：15 May 2024，
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Sheng Bing,Su Yuxin,Chen Rui,et al.Stability study of medical peracetic acid during using period[J].Sterile Supply,2024,03(01):28-32.
DOI：

Sheng Bing,Su Yuxin,Chen Rui,et al.Stability study of medical peracetic acid during using period[J].Sterile Supply,2024,03(01):28-32. DOI： 10.11910/j.issn.2791-2043.2024.1.04.

摘要

Abstract

Objective

To measure the content changes of different brands of peracetic acid (PAA) disinfectants under different conditions of use

and to provide data for stability test of peracetic acid.

Methods

The contents of nine brands of PAA disinfectants after single-use opening

daily opening for one hour

daily sampling and dilution

and daily on-site endoscopic decontamination were measured. Moreover

the PAA contents in three brands of disinfectants were determined after the use cycle was extended to 28 days.

Results

The PAA disinfectants were tested after single-use opening

daily opening for one hour

or daily sampling and dilution. The PAA concentrations in two to three of the nine brands of disinfectants were reduced to less than 1.00 g/L. After daily endoscopic decontamination

the reduction rate of PAA was higher than that of other usage patterns. In this experiment

one PAA disinfectant had good stability

with a content of >1.50 g/L until Day 28.

Conclusion

The endoscopic decontaminator is suitable for evaluating the stability of PAA after continuous use. Moreover

the stability of different PAA disinfectants varies greatly

and some disinfectants may not be able to maintain a qualified effective concentration of PAA for continuous use.

关键词

Keywords

Peracetic acidStability testContent changes

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Stability study of medical peracetic acid during using period

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