1.Xiang'an Hospital of Xiamen University, Xiameng, Fujian, 361102, China
2.Zhongguancun International Medical Inspection and Certification Co., Ltd.
3.Henan Sanqiang Medical Instruments Co., Ltd.
4.Hunan Dongzi Huiyue Medical Technology Co., Ltd.
5.First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510062, China
Scan for full text
Sheng Bing,Su Yu-xin,Chen Rui,et al.Stability study of medical peracetic acid during using period[J].Sterile Supply,2023,02(04):200-204.
Sheng Bing,Su Yu-xin,Chen Rui,et al.Stability study of medical peracetic acid during using period[J].Sterile Supply,2023,02(04):200-204. DOI: 10.11910/j.issn.2791-2043.2023.4.07.
Objective,2,To measure the content changes of different brands of peracetic acid (PAA) disinfectants under different conditions of use, and to provide data for stability test of peracetic acid.,Methods,2,The contents of nine brands of PAA disinfectants after single-use opening, daily opening for one hour, daily sampling and dilution, and daily on-site endoscopic decontamination were measured. Moreover, the PAA contents in three brands of disinfectants were determined after the use cycle was extended to 28 days.,Results,2,The PAA disinfectants were tested after single-use opening, daily opening for one hour, or daily sampling and dilution. The PAA concentrations in two to three of the nine brands of disinfectants were reduced to less than 1.00 g/L. After daily endoscopic decontamination, the reduction rate of PAA was higher than that of other usage patterns. In this experiment, one PAA disinfectant had good stability, with a content of >1.50 g/L until Day 28.,Conclusion,2,The endoscopic decontaminator is suitable for evaluating the stability of PAA after continuous use. Moreover, the stability of different PAA disinfectants varies greatly, and some disinfectants may not be able to maintain a qualified effective concentration of PAA for continuous use.
Peracetic acidStability testContent changes
RUTALA W A, WEBER D J. Disinfection, sterilization, and control of hospital waste[M]//Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases. Amsterdam: Elsevier, 2015: 3294-3309.e4.
KITIS M. Disinfection of wastewater with peracetic acid: a review[J]. Environ Int, 2004, 30(1): 47-55.
DESHPANDE A, MANA T S C, CADNUM J L, et al. Evaluation of a sporicidal peracetic acid/hydrogen peroxide-based daily disinfectant cleaner[J]. Infect Control Hosp Epidemiol, 2014, 35(11): 1414-1416.
DAI Y, CAO QX, WANG CH, et al. Preparation of peroxyacetic acid and tests on its stability and bactericidal effect [J]. Chinese Journal of Disinfection, 1994,11(2):108-109.
Ministry of Health of the People’s Republic of China. Technical Standard For disinfection[S]. 2002.
HOLTON J, SHETTY N. In-use stability of Nu-Cidex[J]. J Hosp Infect, 1997, 35(3): 245-248.
CAO X P, LIU Mengting. Application of FQ-PCR in detecting methicillin-resistant Staphylococcus aureus anti-disinfectant gene[J]. J Mudanjiang Med Univ, 2018, 39(4): 8-10.
JIANG L Q, HAN S H, LI X F, et al. Characteristics of drug resistance and distribution of drug resistance genes of Staphylococcus aureus isolated from postoperative skin and soft tissue infections in orthopedic patients[J]. Chin J Nosocomiology, 2021, 31(20): 3153-3156.
CHEN Y, PEI G D, LI J, et al. Analysis on biofilm forming ability and drug resistance genes of clindamycin-resistant staphylococcus aureus[J]. J Mod Med Health, 2022, 38(1): 11-15.
0
Views
0
Downloads
0
CSCD
Publicity Resources
Related Articles
Related Author
Related Institution